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Acute and postacute sequelae associated with SARS-CoV-2 reinfection

Bowe, B., Xie, Y., Al-Aly, Z.

10 Nov 2022, Nat Med 28, 2398–2405 (2022)

Quote

Compared to no reinfection, reinfection contributed additional risks of death (hazard ratio (HR) = 2.17, 95% confidence intervals (CI) 1.93–2.45), hospitalization (HR = 3.32, 95% CI 3.13–3.51) and sequelae including pulmonary, cardiovascular, hematological, diabetes, gastrointestinal, kidney, mental health, musculoskeletal and neurological disorders. The risks were evident regardless of vaccination status. The risks were most pronounced in the acute phase but persisted in the postacute phase at 6 months.

Interpretation Notes